miRNA in mesothelioma
Limited treatment options in Mesothelioma lead to a short median survival and clinical management is hampered by the lack of molecular biomarkers for diagnosis/prognosis.
There is growing evidence that short non-coding RNAs such as microRNA (miRNA), are useful biomarkers in cancer. Studies at the Institute for Respiratory Health are trying to determine the diagnostic and prognostic potential of miRNAs in serum and pleural effusion fluids and cells from patients with mesothelioma compared with other diseases.
The Institute’s researchers also worked a project seeking to determine if differentially expressed serum miRNAs are early disease markers. miRNA also have important biological roles within cells so we are also looking at the biological significance of certain miRNAs in mesothelioma.
To get involved or for more information, contact the Research Leader.
Dr Cecilia Prêle
BSc (Hons), PhD
Head of Tissue Repair Group