Pleural Effusion and Symptom Evaluation Study (PLEASE)
Pleural effusion is a common clinical problem that can complicate many medical conditions. Breathlessness is the most common symptom of pleural effusion of any cause and the commonest reason for pleural drainage.
However, improvement in breathlessness following drainage of the effusion is variable, with some patients experiencing either no benefit or worsening of their symptoms. The mechanisms underpinning breathlessness in patients with pleural effusions are poorly understood.
The PLEASE study is a prospective study of 100 patients with symptomatic pleural effusions that require therapeutic drainage.
Clinicians at the Institute for Respiratory Health aim to identify key factors that underlie breathlessness in pleural effusion patients and develop predictors of improvement in breathlessness following effusion drainage.
To get involved or for more information, contact the Research Leader.