The hedgehog signalling pathway in mesothelioma
Increasing evidence is pointing to the reactivation and aberrant expression of developmental signalling pathways – such as the hedgehog (Hh) pathway – as critical to the pathogenesis of certain cancers.
Researchers at the Institute for Respiratory Health have undertaken a study which demonstrates that Hh pathway signalling is important in the growth of mesothelioma.
Our teams are examining different antagonists to identify the best possible therapeutic approach to inhibit mesothelioma growth and to help make clear the mechanisms the Hh pathway uses to promote tumour growth.
To get involved or for more information, contact the Research Leader.
Dr Cecilia Prêle
BSc (Hons), PhD
Head of Tissue Repair Group